I've just about finished my first full day using my Cr-48 Chrome Notebook from Google as my primary computer. I have been able to use it for everything I would have done on my regular computer except for two things. I had to use my other computer twice today.
The first thing I couldn't do with the Cr-48 and had to break out my Windows laptop for was to use GoToMeeting this morning for my M-DAT Conference Call. It doesn't look like they have a linux plugin for GoToMeeting yet. I was able to do a test with DimDim and it works just fine.
The second thing I couldn't do with the Cr-48 and had to use my Ubuntu Desktop for was downloading the pictures off the camera. Actually, I downloaded them straight to my Iomega external NAS, but had to use the Ubuntu system to transfer them over the home network and upload them to my Picasa account.
I have read others who were complaining about Flash not running good on the Cr-48, but I have done several tests on YouTube, NFL.com and other sites and have not had any issues with Flash yet. So minus the two issue I mentioned in this post, everything else I have needed a computer for has be accomplished on the Cr-48, living in the cloud!